Erythropoiesis-Stimulating Agents and Heart Failure
نویسندگان
چکیده
منابع مشابه
Erythropoiesis-stimulating agents for anaemia in chronic heart failure patients.
BACKGROUND Chronic heart failure (CHF) is a leading cause of morbidity and mortality worldwide. Anaemia is a common (12-55%) co-morbid condition and is associated with worsening symptoms and increased mortality. Anaemia is treatable and can be targeted in the treatment of patients with CHF. Erythropoiesis-stimulating agents (ESA), supplemented by iron therapy, are used to treat anaemia in chron...
متن کاملAnemia and heart failure: Is there still a role for erythropoiesis-stimulating agents?
A early reports of erythropoiesis-stimulating agents (ESAs) having success correcting anemia in heart failure (HF), the Reduction of Events by Darbepoetin Alfa in Heart Failure (RED-HF) study, a large phase III trial, demonstrated that darbepoetin alfa was not able to improve clinical outcomes in patients with HF who had reduced ejection fraction and mild to moderate anemia, and indeed, it led ...
متن کاملEffects of erythropoiesis-stimulating agents on heart failure patients with anemia: a meta-analysis
INTRODUCTION Heart failure (HF) is always complicated with anemia and is associated with bad prognosis in this patient population. Several studies have assessed the potential role of erythropoietin-stimulating agent (ESA) in improving cardiac function and reducing the number of hospitalizations in anemic patients with HF. AIM We performed a meta-analysis to assess the potential role of ESA in...
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Pharmacovigilance (PV) is the science and activities relating to the detection, assessment, understanding, and prevention of adverse effects or other problems related to medical products after they have been licensed for marketing. The purpose of PV is to advance the safe use of marketed medical products. Regulatory agencies and license holders collaborate to collect data reported by health car...
متن کاملErythropoiesis stimulating agents: a personal journey.
I write this editorial in deference to the many experts who devote their careers to this important field. In this editorial, I simply report the journeyman route of a medical oncologist who is desperately trying to improve the outcomes of women suffering from breast cancer. At the end of the 1990s, there was much hope that erythropoie-sis stimulating agents (ESAs) would improve the survival of ...
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ژورنال
عنوان ژورنال: Cardiovascular Therapeutics
سال: 2010
ISSN: 1755-5914
DOI: 10.1111/j.1755-5922.2010.00240.x